1. Signaling Pathways
  2. Metabolic Enzyme/Protease
    Neuronal Signaling
  3. Adenosine Kinase
  4. Adenosine Kinase Activator

Adenosine Kinase Activator

Adenosine Kinase Activator (1):

Cat. No. Product Name Effect Purity
  • HY-179690
    Antiparasitic agent-30
    Activator
    Antiparasitic agent-30 is a potent adenosine kinase TbrAK modulator and antitrypanosomal agent. Antiparasitic agent-30 exhibits significant inhibitory activity against Trypanosoma brucei rhodesiense, while enhancing the activity of recombinant TbrAK(EC50=38 nM, Ka=75 nM-497 nM). Antiparasitic agent-30 exerts its pharmacological effects by eliminating intrinsic substrate inhibition and hyperactivating TbrAK in Trypanosoma brucei rhodesiense. Antiparasitic agent-30 serves as a valuable tool molecule for studying acute African human trypanosomiasis (sleeping sickness).